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A Unique Spatial Arrangement of the snRNPs within the Native Spliceosome Emerges from In-Silico Studies

The spliceosome is a mega-Dalton ribonucleoprotein (RNP) assembly that processes primary RNA transcripts, producing functional mRNA. The electron microscopy structures of the native spliceosome and of several spliceosomal subcomplexes are available but the spatial arrangement of the latter within th...

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Autors principals: Frankenstein, Ziv, Sperling, Joseph, Sperling, Ruth, Eisenstein, Miriam
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372696/
https://ncbi.nlm.nih.gov/pubmed/22578543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.03.022
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