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A Unique Spatial Arrangement of the snRNPs within the Native Spliceosome Emerges from In-Silico Studies
The spliceosome is a mega-Dalton ribonucleoprotein (RNP) assembly that processes primary RNA transcripts, producing functional mRNA. The electron microscopy structures of the native spliceosome and of several spliceosomal subcomplexes are available but the spatial arrangement of the latter within th...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3372696/ https://ncbi.nlm.nih.gov/pubmed/22578543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.03.022 |
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