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RNA-binding proteins in microsatellite expansion disorders: mediators of RNA toxicity
Although protein-mediated toxicity in neurological disease has been extensively characterized, RNA-mediated toxicity is an emerging mechanism of pathogenesis. In microsatellite expansion disorders, expansion of repeated sequences in noncoding regions gives rise to RNA that produces a toxic gain of f...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3372679/ https://ncbi.nlm.nih.gov/pubmed/22405728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.02.030 |
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