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RNA-binding proteins in microsatellite expansion disorders: mediators of RNA toxicity
Although protein-mediated toxicity in neurological disease has been extensively characterized, RNA-mediated toxicity is an emerging mechanism of pathogenesis. In microsatellite expansion disorders, expansion of repeated sequences in noncoding regions gives rise to RNA that produces a toxic gain of f...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3372679/ https://ncbi.nlm.nih.gov/pubmed/22405728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.02.030 |
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