The Three-Dimensional Structural Basis of Type II Hyperprolinemia

Type II hyperprolinemia is an autosomal recessive disorder caused by a deficiency in Δ(1)-pyrroline-5-carboxylate dehydrogenase (P5CDH, aka ALDH4A1), the aldehyde dehydrogenase that catalyzes the oxidation of glutamate semialdehyde to glutamate. Here we report the first structure of human P5CDH and...

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Detaylı Bibliyografya
Asıl Yazarlar: Srivastava, Dhiraj, Singh, Ranjan K., Moxley, Michael A., Henzl, Michael T., Becker, Donald F., Tanner, John J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372638/
https://ncbi.nlm.nih.gov/pubmed/22516612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.04.010
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