The Three-Dimensional Structural Basis of Type II Hyperprolinemia

Type II hyperprolinemia is an autosomal recessive disorder caused by a deficiency in Δ(1)-pyrroline-5-carboxylate dehydrogenase (P5CDH, aka ALDH4A1), the aldehyde dehydrogenase that catalyzes the oxidation of glutamate semialdehyde to glutamate. Here we report the first structure of human P5CDH and...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Srivastava, Dhiraj, Singh, Ranjan K., Moxley, Michael A., Henzl, Michael T., Becker, Donald F., Tanner, John J.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372638/
https://ncbi.nlm.nih.gov/pubmed/22516612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.04.010
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares