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Anti-inflammatory effect of simvastatin in an experimental model of spinal cord trauma: involvement of PPAR-α
BACKGROUND: Statins such as simvastatin are inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase used in the prevention of cardiovascular disease. In addition to their cholesterol-lowering activities, statins exert pleiotropic anti-inflammatory effects, which might contribute to t...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3372420/ https://ncbi.nlm.nih.gov/pubmed/22537532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-81 |
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