PPARα mediates the anti-inflammatory effect of simvastatin in an experimental model of zymosan-induced multiple organ failure

BACKGROUND AND PURPOSE: Zymosan-induced non-septic shock is a multi-factorial pathology that involves several organs including the kidneys, liver and lungs. Its complexity and diversity presents a continuing therapeutic challenge. Given their pleiotropic effect, statins could be beneficial in non-se...

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Detalhes bibliográficos
Main Authors: Rinaldi, Barbara, Donniacuo, Maria, Esposito, Emanuela, Capuano, Annalisa, Sodano, Loredana, Mazzon, Emanuela, Di Palma, Donatella, Paterniti, Irene, Cuzzocrea, Salvatore, Rossi, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101622/
https://ncbi.nlm.nih.gov/pubmed/21323892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01248.x
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