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hnRNP Q Regulates Cdc42-Mediated Neuronal Morphogenesis

The RNA-binding protein hnRNP Q has been implicated in neuronal mRNA metabolism. Here, we show that knockdown of hnRNP Q increased neurite complexity in cultured rat cortical neurons and induced filopodium formation in mouse neuroblastoma cells. Reexpression of hnRNP Q1 in hnRNP Q-depleted cells abr...

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Autors principals: Chen, Hung-Hsi, Yu, Hsin-I, Chiang, Wen-Cheng, Lin, Yu-De, Shia, Ben-Chang, Tarn, Woan-Yuh
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372263/
https://ncbi.nlm.nih.gov/pubmed/22493061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06550-11
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