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Rapid Cytoplasmic Turnover of Yeast Ribosomes in Response to Rapamycin Inhibition of TOR

The target of rapamycin (TOR) pathway is the central regulator of cell growth in eukaryotes. Inhibition of TOR by rapamycin elicits changes in translation attributed mainly to altered translation initiation and repression of the synthesis of new ribosomes. Using quantitative analysis of rRNA, we fou...

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Main Authors: Pestov, Dimitri G., Shcherbik, Natalia
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372233/
https://ncbi.nlm.nih.gov/pubmed/22451491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06763-11
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