Molecular Genetic and Biochemical Characterization of the Vaccinia Virus I3 Protein, the Replicative Single-Stranded DNA Binding Protein

Vaccinia virus, the prototypic poxvirus, efficiently and faithfully replicates its ∼200-kb DNA genome within the cytoplasm of infected cells. This intracellular localization dictates that vaccinia virus encodes most, if not all, of its own DNA replication machinery. Included in the repertoire of vir...

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Detalhes bibliográficos
Main Authors: Greseth, Matthew D., Boyle, Kathleen A., Bluma, Matthew S., Unger, Bethany, Wiebe, Matthew S., Soares-Martins, Jamaria A., Wickramasekera, Nadi T., Wahlberg, James, Traktman, Paula
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372221/
https://ncbi.nlm.nih.gov/pubmed/22438556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00206-12
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