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Biochemical and Genetic Analysis of the Vaccinia Virus D5 Protein: Multimerization-Dependent ATPase Activity Is Required To Support Viral DNA Replication

The vaccinia virus-encoded D5 protein is an essential ATPase involved in viral DNA replication. We have expanded the genotypic and phenotypic analysis of six temperature-sensitive (ts) D5 mutants (Cts17, Cts24, Ets69, Dts6389 [also referred to as Dts38], Dts12, and Dts56) and shown that at nonpermis...

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Detalhes bibliográficos
Main Authors: Boyle, Kathleen A., Arps, Lisa, Traktman, Paula
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797480/
https://ncbi.nlm.nih.gov/pubmed/17093187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02217-06
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