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Isolation and Characterization of vΔI3 Confirm that Vaccinia Virus SSB Plays an Essential Role in Viral Replication

Vaccinia virus is unusual among DNA viruses in replicating exclusively in the cytoplasm of infected cells. The single-stranded DNA (ssDNA) binding protein (SSB) I3 is among the replication machinery encoded by the 195-kb genome, although direct genetic analysis of I3 has been lacking. Herein, we des...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Greseth, Matthew D., Czarnecki, Maciej W., Bluma, Matthew S., Traktman, Paula
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752924/
https://ncbi.nlm.nih.gov/pubmed/29093092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01719-17
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