Blockade of TGF-β 1 Signalling Inhibits Cardiac NADPH Oxidase Overactivity in Hypertensive Rats

NADPH oxidases constitute a major source of superoxide anion (·O(2) (−)) in hypertension. Several studies suggest an important role of NADPH oxidases in different effects mediated by TGF-β 1. In this study we show that chronic administration of P144, a peptide synthesized from type III TGF-β 1 recep...

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Main Authors: Miguel-Carrasco, José Luis, Baltanás, Ana, Cebrián, Carolina, Moreno, María U., López, Begoña, Hermida, Nerea, González, Arantxa, Dotor, Javier, Borrás-Cuesta, Francisco, Díez, Javier, Fortuño, Ana, Zalba, Guillermo
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372069/
https://ncbi.nlm.nih.gov/pubmed/22701756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/726940
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