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NADPH oxidase-dependent redox signaling in TGF-β-mediated fibrotic responses

Uncontrolled fibrosis in organs like heart, kidney, liver and lung is detrimental and may lead to end-stage organ failure. Currently there is no effective treatment for fibrotic disorders. Transforming growth factor (TGF)-β has a fundamental role in orchestrating the process of fibrogenesis; however...

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Detalhes bibliográficos
Main Authors: Fan Jiang, Guei-Sheung Liu, Gregory J. Dusting, Elsa C. Chan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014-01-01
Colecção:Redox Biology
Assuntos:
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2213231714000275
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