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Role of C3, C5 and Anaphylatoxin Receptors in Acute Lung Injury and in Sepsis

The complement system plays a major role in innate immune defenses against infectious agents, but exaggerated activation of complement can lead to severe tissue injury. Systemic (intravascular) activation of complement can, via C5a, lead to neutrophil (PMN) activation, sequestration and adhesion to...

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Bibliographic Details
Main Authors: Bosmann, Markus, Ward, Peter A.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372066/
https://ncbi.nlm.nih.gov/pubmed/21948367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4614-0106-3_9
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