Functional roles for C5a receptors in sepsis

The function of the C5a receptors, C5ar (encoded by C5ar) and C5l2 (encoded by Gpr77), especially of C5l2, which was originally termed a ‘default receptor’, remains a controversial topic. Here we investigated the role of each receptor in the setting of cecal ligation and puncture-induced sepsis by u...

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Main Authors: Rittirsch, Daniel, Flierl, Michael A, Nadeau, Brian A, Day, Danielle E, Huber-Lang, Markus, Mackay, Charles R, Zetoune, Firas S, Gerard, Norma P, Cianflone, Katherine, Köhl, Jörg, Gerard, Craig, Sarma, J Vidya, Ward, Peter A
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753858/
https://ncbi.nlm.nih.gov/pubmed/18454156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1753
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