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Functions of the complement components C3 and C5 during sepsis

Activation of the complement system is a key event in the pathogenesis of sepsis. Nevertheless, the exact mechanisms remain inadequately understood. In the current study, we examined the role of complement C3 and C5 in sepsis in wild-type and C3- or C5-deficient mice induced by cecal ligation and pu...

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Bibliografische gegevens
Hoofdauteurs: Flierl, Michael A., Rittirsch, Daniel, Nadeau, Brian A., Day, Danielle E., Zetoune, Firas S., Sarma, J. Vidya, Huber-Lang, Markus S., Ward, Peter A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Federation of American Societies for Experimental Biology 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2537435/
https://ncbi.nlm.nih.gov/pubmed/18587006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-110595
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