Functions of the complement components C3 and C5 during sepsis

Activation of the complement system is a key event in the pathogenesis of sepsis. Nevertheless, the exact mechanisms remain inadequately understood. In the current study, we examined the role of complement C3 and C5 in sepsis in wild-type and C3- or C5-deficient mice induced by cecal ligation and pu...

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Detalhes bibliográficos
Main Authors: Flierl, Michael A., Rittirsch, Daniel, Nadeau, Brian A., Day, Danielle E., Zetoune, Firas S., Sarma, J. Vidya, Huber-Lang, Markus S., Ward, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2008
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2537435/
https://ncbi.nlm.nih.gov/pubmed/18587006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-110595
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