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Role of C3, C5 and Anaphylatoxin Receptors in Acute Lung Injury and in Sepsis

The complement system plays a major role in innate immune defenses against infectious agents, but exaggerated activation of complement can lead to severe tissue injury. Systemic (intravascular) activation of complement can, via C5a, lead to neutrophil (PMN) activation, sequestration and adhesion to...

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Détails bibliographiques
Auteurs principaux: Bosmann, Markus, Ward, Peter A.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372066/
https://ncbi.nlm.nih.gov/pubmed/21948367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4614-0106-3_9
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