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Role of C3, C5 and Anaphylatoxin Receptors in Acute Lung Injury and in Sepsis
The complement system plays a major role in innate immune defenses against infectious agents, but exaggerated activation of complement can lead to severe tissue injury. Systemic (intravascular) activation of complement can, via C5a, lead to neutrophil (PMN) activation, sequestration and adhesion to...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3372066/ https://ncbi.nlm.nih.gov/pubmed/21948367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4614-0106-3_9 |
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