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A single source k-shortest paths algorithm to infer regulatory pathways in a gene network

Motivation: Inferring the underlying regulatory pathways within a gene interaction network is a fundamental problem in Systems Biology to help understand the complex interactions and the regulation and flow of information within a system-of-interest. Given a weighted gene network and a gene in this...

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Detalhes bibliográficos
Main Authors: Shih, Yu-Keng, Parthasarathy, Srinivasan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371844/
https://ncbi.nlm.nih.gov/pubmed/22689778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts212
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