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Statistical model-based testing to evaluate the recurrence of genomic aberrations

Motivation: In cancer genomes, chromosomal regions harboring cancer genes are often subjected to genomic aberrations like copy number alteration and loss of heterozygosity. Given this, finding recurrent genomic aberrations is considered an apt approach for screening cancer genes. Although several pe...

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Bibliografiske detaljer
Main Authors: Niida, Atushi, Imoto, Seiya, Shimamura, Teppei, Miyano, Satoru
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371835/
https://ncbi.nlm.nih.gov/pubmed/22689750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts203
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