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Statistical model-based testing to evaluate the recurrence of genomic aberrations
Motivation: In cancer genomes, chromosomal regions harboring cancer genes are often subjected to genomic aberrations like copy number alteration and loss of heterozygosity. Given this, finding recurrent genomic aberrations is considered an apt approach for screening cancer genes. Although several pe...
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Main Authors: | , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
Oxford University Press
2012
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3371835/ https://ncbi.nlm.nih.gov/pubmed/22689750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts203 |
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