Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac–derived macrophages

Langerhans cells (LCs) are the dendritic cells (DCs) of the epidermis, forming one of the first hematopoietic lines of defense against skin pathogens. In contrast to other DCs, LCs arise from hematopoietic precursors that seed the skin before birth. However, the origin of these embryonic precursors...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hoeffel, Guillaume, Wang, Yilin, Greter, Melanie, See, Peter, Teo, Pearline, Malleret, Benoit, Leboeuf, Marylène, Low, Donovan, Oller, Guillaume, Almeida, Francisca, Choy, Sharon H.Y., Grisotto, Marcos, Renia, Laurent, Conway, Simon J., Stanley, E. Richard, Chan, Jerry K.Y., Ng, Lai Guan, Samokhvalov, Igor M., Merad, Miriam, Ginhoux, Florent
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371735/
https://ncbi.nlm.nih.gov/pubmed/22565823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120340
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