Epidermal γδ T cells originate from yolk sac hematopoiesis and clonally self-renew in the adult

The murine epidermis harbors two immune cell lineages, Langerhans cells (LCs) and γδ T cells known as dendritic epidermal T cells (DETCs). LCs develop from both early yolk sac (YS) progenitors and fetal liver monocytes before locally self-renewing in the adult. For DETCs, the mechanisms of homeostat...

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Dettagli Bibliografici
Pubblicato in:J Exp Med
Autori principali: Gentek, Rebecca, Ghigo, Clément, Hoeffel, Guillaume, Jorquera, Audrey, Msallam, Rasha, Wienert, Stephan, Klauschen, Frederick, Ginhoux, Florent, Bajénoff, Marc
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2018
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279412/
https://ncbi.nlm.nih.gov/pubmed/30409784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181206
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