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A new disease-specific machine learning approach for the prediction of cancer-causing missense variants

High-throughput genotyping and sequencing techniques are rapidly and inexpensively providing large amounts of human genetic variation data. Single Nucleotide Polymorphisms (SNPs) are an important source of human genome variability and have been implicated in several human diseases, including cancer....

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Bibliographic Details
Main Authors: Capriotti, Emidio, Altman, Russ B.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371640/
https://ncbi.nlm.nih.gov/pubmed/21763417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2011.06.010
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