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MVP predicts the pathogenicity of missense variants by deep learning

Accurate pathogenicity prediction of missense variants is critically important in genetic studies and clinical diagnosis. Previously published prediction methods have facilitated the interpretation of missense variants but have limited performance. Here, we describe MVP (Missense Variant Pathogenici...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Qi, Hongjian, Zhang, Haicang, Zhao, Yige, Chen, Chen, Long, John J., Chung, Wendy K., Guan, Yongtao, Shen, Yufeng
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820281/
https://ncbi.nlm.nih.gov/pubmed/33479230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20847-0
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