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Prediction of calcium-binding sites by combining loop-modeling with machine learning

BACKGROUND: Protein ligand-binding sites in the apo state exhibit structural flexibility. This flexibility often frustrates methods for structure-based recognition of these sites because it leads to the absence of electron density for these critical regions, particularly when they are in surface loo...

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Detalhes bibliográficos
Main Authors: Liu, Tianyun, Altman, Russ B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808310/
https://ncbi.nlm.nih.gov/pubmed/20003365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-9-72
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