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Mechanisms underlying reductant-induced reactive oxygen species formation by anticancer copper(II) compounds

Intracellular generation of reactive oxygen species (ROS) via thiol-mediated reduction of copper(II) to copper(I) has been assumed as the major mechanism underlying the anticancer activity of copper(II) complexes. The aim of this study was to compare the anticancer potential of copper(II) complexes...

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Autori principali: Kowol, Christian R., Heffeter, Petra, Miklos, Walter, Gille, Lars, Trondl, Robert, Cappellacci, Loredana, Berger, Walter, Keppler, Bernhard K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371635/
https://ncbi.nlm.nih.gov/pubmed/22189939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-011-0864-x
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