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A practical guide to modelling enzyme-catalysed reactions

Molecular modelling and simulation methods are increasingly at the forefront of elucidating mechanisms of enzyme-catalysed reactions, and shedding light on the determinants of specificity and efficiency of catalysis. These methods have the potential to assist in drug discovery and the design of nove...

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Detalhes bibliográficos
Main Authors: Lonsdale, Richard, Harvey, Jeremy N., Mulholland, Adrian J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371381/
https://ncbi.nlm.nih.gov/pubmed/22278388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cs15297e
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