Assessing Disease Risk in Genome-wide Association Studies Using Family History

We show how to use reports of cancer in family members to discover additional genetic associations or confirm previous findings in genome-wide association (GWA) studies conducted in case-control, cohort, or cross-sectional studies. Our novel family-history-based approach allows economical associatio...

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Main Authors: Ghosh, Arpita, Hartge, Patricia, Purdue, Mark P., Chanock, Stephen J., Amundadottir, Laufey, Wang, Zhaoming, Wentzensen, Nicolas, Chatterjee, Nilanjan, Wacholder, Sholom
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371359/
https://ncbi.nlm.nih.gov/pubmed/22575968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/EDE.0b013e31825583a0
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