Peptide mimotopes of malondialdehyde epitopes for clinical applications in cardiovascular disease

Autoantibodies specific for malondialdehyde-modified LDL (MDA-LDL) represent potential biomarkers to predict cardiovascular risk. However, MDA-LDL is a high variability antigen with limited reproducibility. To identify peptide mimotopes of MDA-LDL, phage display libraries were screened with the MDA-...

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Main Authors: Amir, Shahzada, Hartvigsen, Karsten, Gonen, Ayelet, Leibundgut, Gregor, Que, Xuchu, Jensen-Jarolim, Erika, Wagner, Oswald, Tsimikas, Sotirios, Witztum, Joseph L., Binder, Christoph J.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2012
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371243/
https://ncbi.nlm.nih.gov/pubmed/22508944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M025445
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