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Oxidation-specific epitopes and immunological responses: Translational biotheranostic implications for atherosclerosis

Oxidation-specific epitopes (OSE), present on oxidized LDL (OxLDL), apoptotic cells, cell debris and modified proteins in the vessel wall, accumulate in response to hypercholesterolemia, and generate potent pro-inflammatory, disease-specific antigens. They represent an important class of ‘danger ass...

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Detalhes bibliográficos
Main Authors: Leibundgut, Gregor, Witztum, Joseph L, Tsimikas, Sotirios
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844667/
https://ncbi.nlm.nih.gov/pubmed/23541680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2013.02.005
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