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Expression, purification, crystallization and preliminary X-ray analysis of Plasmodium falciparum GTP:AMP phosphotransferase

Adenylate kinases (AKs) are phosphotransferase enzymes that catalyze the interconversion of adenine nucleotides, thereby playing an important role in energy metabolism. In Plasmodium falciparum, three AK isoforms, namely PfAK1, PfAK2 and GTP:AMP phosphotransferase (PfGAK), have been identified. Whil...

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Hlavní autoři: Law, Alan W. L., Lescar, Julien, Hao, Quan, Kotaka, Masayo
Médium: Artigo
Jazyk:Inglês
Vydáno: International Union of Crystallography 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370907/
https://ncbi.nlm.nih.gov/pubmed/22684067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112015862
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