Apicoplast-Targeting Antibacterials Inhibit the Growth of Babesia Parasites

The apicoplast housekeeping machinery, specifically apicoplast DNA replication, transcription, and translation, was targeted by ciprofloxacin, thiostrepton, and rifampin, respectively, in the in vitro cultures of four Babesia species. Furthermore, the in vivo effect of thiostrepton on the growth cyc...

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Detalhes bibliográficos
Main Authors: AbouLaila, Mahmoud, Munkhjargal, Tserendorj, Sivakumar, Thillaiampalam, Ueno, Akio, Nakano, Yuki, Yokoyama, Miki, Yoshinari, Takeshi, Nagano, Daisuke, Katayama, Koji, El-Bahy, Nasr, Yokoyama, Naoaki, Igarashi, Ikuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370714/
https://ncbi.nlm.nih.gov/pubmed/22391527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05488-11
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