Clofazimine Inhibits the Growth of Babesia and Theileria Parasites In Vitro and In Vivo

The present study evaluated the growth-inhibitory effects of clofazimine, currently used for treating leprosy, against Babesia bovis, B. bigemina, B. caballi, and Theileria equi in in vitro culture and against Babesia microti in mice. The 50% inhibitory concentrations (IC(50)s) of clofazimine agains...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Tuvshintulga, Bumduuren, AbouLaila, Mahmoud, Davaasuren, Batdorj, Ishiyama, Aki, Sivakumar, Thillaiampalam, Yokoyama, Naoaki, Iwatsuki, Masato, Otoguro, Kazuhiko, Ōmura, Satoshi, Igarashi, Ikuo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862543/
https://ncbi.nlm.nih.gov/pubmed/26883713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01614-15
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