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Inhibition of adenovirus multiplication by short interfering RNAs directly or indirectly targeting the viral DNA replication machinery

Human adenoviruses are a common threat to immunocompromised patients, e.g., HIV-positive individuals or solid-organ and, in particular, allogeneic stem cell transplant recipients. Antiviral drugs have a limited effect on adenoviruses, and existing treatment modalities often fail to prevent fatal out...

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Detalhes bibliográficos
Main Authors: Kneidinger, Doris, Ibrišimović, Mirza, Lion, Thomas, Klein, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370646/
https://ncbi.nlm.nih.gov/pubmed/22510340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2012.03.011
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