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Regulation of Cytokine and Chemokine Expression by the Ribotoxic Stress Response Elicited by Shiga Toxin Type 1 in Human Macrophage-Like THP-1 Cells

Shiga toxins (Stxs) are cytotoxins produced by the enteric pathogens Shigella dysenteriae serotype 1 and Shiga toxin-producing Escherichia coli (STEC). Stxs bind to a membrane glycolipid receptor, enter cells, and undergo retrograde transport to ultimately reach the cytosol, where the toxins exert t...

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Bibliografski detalji
Glavni autori: Leyva-Illades, Dinorah, Cherla, Rama P., Lee, Moo-Seung, Tesh, Vernon L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370584/
https://ncbi.nlm.nih.gov/pubmed/22431646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.06025-11
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