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Simultaneous Induction of Apoptotic and Survival Signaling Pathways in Macrophage-Like THP-1 Cells by Shiga Toxin 1

Shiga toxins have been shown to induce apoptosis in many cell types. However, Shiga toxin 1 (Stx1) induced only limited apoptosis of macrophage-like THP-1 cells in vitro. The mechanisms regulating macrophage death or survival following toxin challenge are unknown. Differentiated THP-1 cells expresse...

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Autors principals: Lee, Sang-Yun, Cherla, Rama P., Tesh, Vernon L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828570/
https://ncbi.nlm.nih.gov/pubmed/17194804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01700-06
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