Shiga Toxin 1 Induces Apoptosis in the Human Myelogenous Leukemia Cell Line THP-1 by a Caspase-8-Dependent, Tumor Necrosis Factor Receptor-Independent Mechanism

Shiga toxins (Stxs) induce apoptosis in a variety of cell types. Here, we show that Stx1 induces apoptosis in the undifferentiated myelogenous leukemia cell line THP-1 in the absence of tumor necrosis factor alpha (TNF-α) or death receptor (TNF receptor or Fas) expression. Caspase-8 and -3 inhibitor...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lee, Sang-Yun, Cherla, Rama P., Caliskan, Isa, Tesh, Vernon L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201203/
https://ncbi.nlm.nih.gov/pubmed/16041028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.8.5115-5126.2005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados