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Signaling through C/EBP Homologous Protein and Death Receptor 5 and Calpain Activation Differentially Regulate THP-1 Cell Maturation-Dependent Apoptosis Induced by Shiga Toxin Type 1

Shiga toxins (Stxs) induce apoptosis via activation of the intrinsic and extrinsic pathways in many cell types. Toxin-mediated activation of the endoplasmic reticulum (ER) stress response was shown to be instrumental in initiating apoptosis in THP-1 myeloid leukemia cells. THP-1 cells responded to S...

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Detalhes bibliográficos
Main Authors: Lee, Moo-Seung, Cherla, Rama P., Lentz, Erin K., Leyva-Illades, Dinorah, Tesh, Vernon L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916263/
https://ncbi.nlm.nih.gov/pubmed/20515924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00342-10
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