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Shiga toxins induce autophagy leading to differential signaling pathways in toxin-sensitive and toxin-resistant human cells
The bacterial virulence factors Shiga toxins (Stxs) are expressed by Shigella dysenteriae serotype 1 and certain Escherichia coli strains. Stxs are protein synthesis inhibitors and induce apoptosis in many cell types. Stxs induce apoptosis via prolonged ER stress signaling to activate both extrinsic...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173519/ https://ncbi.nlm.nih.gov/pubmed/21722286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2011.01634.x |
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