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Shiga toxins induce autophagy leading to differential signaling pathways in toxin-sensitive and toxin-resistant human cells

The bacterial virulence factors Shiga toxins (Stxs) are expressed by Shigella dysenteriae serotype 1 and certain Escherichia coli strains. Stxs are protein synthesis inhibitors and induce apoptosis in many cell types. Stxs induce apoptosis via prolonged ER stress signaling to activate both extrinsic...

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Detaylı Bibliyografya
Asıl Yazarlar: Lee, Moo-Seung, Cherla, Rama P., Jenson, Matthew H., Leyva-Illades, Dinorah, Martinez-Moczygemba, Margarita, Tesh, Vernon L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173519/
https://ncbi.nlm.nih.gov/pubmed/21722286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2011.01634.x
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