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High-Throughput Screening for Streptomyces Antibiotic Biosynthesis Activators
A genomic cosmid library of Streptomyces clavuligerus was constructed and transferred efficiently by conjugation to Streptomyces lividans, and 12 distinct groups of overlapping cosmid clones that activated the silent actinorhodin biosynthesis gene cluster were identified. This generally applicable h...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3370547/ https://ncbi.nlm.nih.gov/pubmed/22504805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00348-12 |
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