Precise Manipulation of the Clostridium difficile Chromosome Reveals a Lack of Association between the tcdC Genotype and Toxin Production

Clostridium difficile causes a potentially fatal diarrheal disease through the production of its principal virulence factors, toxin A and toxin B. The tcdC gene is thought to encode a negative regulator of toxin production. Therefore, increased toxin production, and hence increased virulence, is oft...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cartman, Stephen T., Kelly, Michelle L., Heeg, Daniela, Heap, John T., Minton, Nigel P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2012
Gaiak:
Genetics and Molecular Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370502/
https://ncbi.nlm.nih.gov/pubmed/22522680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00249-12
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