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Role of telomeres and telomerase in cancer

There is mounting evidence for the existence of an important relationship between telomeres and telomerase and cellular aging and cancer. Normal human cells progressively lose telomeres with each cell division until a few short telomeres become uncapped leading to a growth arrest known as replicativ...

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Detalhes bibliográficos
Main Authors: Shay, Jerry W., Wright, Woodring E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370415/
https://ncbi.nlm.nih.gov/pubmed/22015685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2011.10.001
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