Fas Ligand Enhances Malignant Behavior of Tumor Cells through Interaction with Met, Hepatocyte Growth Factor Receptor, in Lipid Rafts

Many late-stage cancer cells express Fas ligand (FasL) and show high malignancy with metastatic potential. We report here a novel signaling mechanism for FasL that hijacks the Met signal pathway to promote tumor metastasis. FasL-expressing human tumor cells express a significant amount of phosphoryl...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Lin, Huan-Ching, Lai, Po-Yin, Lin, Yu-ping, Huang, Jyun-Yuan, Yang, Bei-Chang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370249/
https://ncbi.nlm.nih.gov/pubmed/22535954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.326058
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares