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Calmodulin phosphorylation and modulation of endothelial nitric oxide synthase catalysis

The endothelial NO synthase (eNOS) is regulated by diverse protein kinase pathways, yet eNOS activity ultimately depends on the ubiquitous calcium regulatory protein calmodulin (CaM). In these studies, we establish that CaM itself undergoes phosphorylation in endothelial cells and that CaM phosphory...

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Detalhes bibliográficos
Main Authors: Greif, Daniel M., Sacks, David B., Michel, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC337024/
https://ncbi.nlm.nih.gov/pubmed/14736917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306377101
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