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Isometric contraction induces the Ca(2+)-independent activation of the endothelial nitric oxide synthase

Shear stress and tyrosine phosphatase inhibitors have been shown to activate the endothelial NO synthase (eNOS) in a Ca(2+)/calmodulin-independent manner. We report here that isometric contraction of rabbit aorta activates eNOS by a pharmacologically identical pathway. Endothelium-intact aortic ring...

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Bibliografiske detaljer
Main Authors: Fleming, Ingrid, Bauersachs, Johann, Schäfer, Andreas, Scholz, Dimitri, Aldershvile, Jan, Busse, Rudi
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC15361/
https://ncbi.nlm.nih.gov/pubmed/9927704
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