Isometric contraction induces the Ca(2+)-independent activation of the endothelial nitric oxide synthase
Shear stress and tyrosine phosphatase inhibitors have been shown to activate the endothelial NO synthase (eNOS) in a Ca(2+)/calmodulin-independent manner. We report here that isometric contraction of rabbit aorta activates eNOS by a pharmacologically identical pathway. Endothelium-intact aortic ring...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
1999
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15361/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9927704/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.3.1123 |
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