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Calmodulin phosphorylation and modulation of endothelial nitric oxide synthase catalysis

The endothelial NO synthase (eNOS) is regulated by diverse protein kinase pathways, yet eNOS activity ultimately depends on the ubiquitous calcium regulatory protein calmodulin (CaM). In these studies, we establish that CaM itself undergoes phosphorylation in endothelial cells and that CaM phosphory...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Greif, Daniel M., Sacks, David B., Michel, Thomas
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC337024/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14736917/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0306377101
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