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Calmodulin phosphorylation and modulation of endothelial nitric oxide synthase catalysis

The endothelial NO synthase (eNOS) is regulated by diverse protein kinase pathways, yet eNOS activity ultimately depends on the ubiquitous calcium regulatory protein calmodulin (CaM). In these studies, we establish that CaM itself undergoes phosphorylation in endothelial cells and that CaM phosphory...

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Autori principali: Greif, Daniel M., Sacks, David B., Michel, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC337024/
https://ncbi.nlm.nih.gov/pubmed/14736917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306377101
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